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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
20
Human Site:
S243
Identified Species:
27.5
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
S243
D
R
Q
S
N
T
P
S
P
P
V
S
T
F
S
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
S243
D
R
Q
S
N
T
P
S
P
P
V
S
T
F
S
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
S242
D
R
Q
S
N
T
P
S
P
P
V
S
T
F
S
Dog
Lupus familis
XP_533766
1089
122761
P241
Q
S
N
T
P
S
P
P
I
S
T
F
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
P241
Q
S
N
T
P
S
P
P
V
S
S
F
S
S
G
Rat
Rattus norvegicus
NP_446123
1093
121882
P242
Q
S
N
T
P
S
P
P
V
S
S
F
S
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
S249
D
R
Q
S
N
T
P
S
P
P
I
S
T
F
S
Chicken
Gallus gallus
O42184
1433
161009
S341
T
G
L
L
T
E
T
S
S
R
Y
A
R
K
I
Frog
Xenopus laevis
Q5PQ23
649
75475
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
S269
D
R
Q
S
D
T
P
S
P
P
V
S
A
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
K193
D
H
L
N
D
S
T
K
T
M
K
A
L
V
L
Honey Bee
Apis mellifera
XP_394037
1326
150590
V282
P
D
S
D
S
C
S
V
S
N
L
A
S
P
A
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
S874
K
V
K
A
L
E
D
S
L
A
K
E
E
K
L
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
E248
S
L
Q
E
T
K
S
E
D
S
A
I
N
P
E
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
S236
S
T
I
Q
A
E
V
S
N
E
P
Q
P
E
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
D217
E
V
T
V
E
N
K
D
T
V
H
S
P
V
L
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
100
6.6
N.A.
6.6
6.6
N.A.
93.3
6.6
0
86.6
N.A.
6.6
0
6.6
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
26.6
26.6
N.A.
100
13.3
0
93.3
N.A.
33.3
33.3
20
6.6
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
6
6
0
0
0
0
6
6
18
6
0
12
% A
% Cys:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% C
% Asp:
36
6
0
6
12
0
6
6
6
0
0
0
0
0
0
% D
% Glu:
6
0
0
6
6
18
0
6
0
6
0
6
6
6
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
18
0
30
0
% F
% Gly:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
18
% G
% His:
0
6
0
0
0
0
0
0
0
0
6
0
0
0
0
% H
% Ile:
0
0
6
0
0
0
0
0
6
0
6
6
0
0
6
% I
% Lys:
6
0
6
0
0
6
6
6
0
0
12
0
0
12
0
% K
% Leu:
0
6
12
6
6
0
0
0
6
0
6
0
6
0
18
% L
% Met:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% M
% Asn:
0
0
18
6
24
6
0
0
6
6
0
0
6
0
0
% N
% Pro:
6
0
0
0
18
0
48
18
30
30
6
0
12
12
0
% P
% Gln:
18
0
36
6
0
0
0
0
0
0
0
6
0
0
0
% Q
% Arg:
0
30
0
0
0
0
0
0
0
6
0
0
6
0
0
% R
% Ser:
12
18
6
30
6
24
12
48
12
24
12
36
24
18
30
% S
% Thr:
6
6
6
18
12
30
12
0
12
0
6
0
24
0
0
% T
% Val:
0
12
0
6
0
0
6
6
12
6
24
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _